IL-1R8 Deficiency Drives Autoimmunity-Associated Lymphoma Development

Chronic inflammation, including that driven by autoimmunity, is associated with development of B-cell lymphomas. IL-1R8 is a regulatory receptor belonging to the IL-1R family, which negatively regulates NF-κB activation following stimulation of IL-1R or Toll Like Receptor (TLR) family members. IL-1R...

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Udgivet i:Cancer Immunol Res
Main Authors: Riva, Federica, Ponzoni, Maurilio, Supino, Domenico, Bertilaccio, Maria Teresa Sabrina, Polentarutti, Nadia, Massara, Matteo, Pasqualini, Fabio, Carriero, Roberta, Innocenzi, Anna, Anselmo, Achille, Veliz-Rodriguez, Tania, Simonetti, Giorgia, Anders, Hans-Joachim, Caligaris-Cappio, Federico, Mantovani, Alberto, Muzio, Marta, Garlanda, Cecilia
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176492/
https://ncbi.nlm.nih.gov/pubmed/31018956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0698
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