Nascent HDL (High-Density Lipoprotein) Discs Carry Cholesterol to HDL Spheres: Effects of HDL Particle Remodeling on Cholesterol Efflux

OBJECTIVE: To characterize the fate of protein and lipid in nascent HDL (high-density lipoprotein) in plasma and explore the role of interaction between nascent HDL and mature HDL in promoting ABCA1 (ATP-binding cassette transporter 1)-dependent cholesterol efflux. APPROACH AND RESULTS: Two discoida...

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Bibliographic Details
Published in:Arterioscler Thromb Vasc Biol
Main Authors: Navdaev, Alexei V., Sborgi, Lorenzo, Wright, Samuel D., Didichenko, Svetlana A.
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2020
Subjects:
Basic Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176342/
https://ncbi.nlm.nih.gov/pubmed/32131613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.313906
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