Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112: Effects on Cholesterol Efflux, Anti-Inflammatory and Antioxidative Activity

RATIONALE: CSL112, human apolipoprotein A-I (apoA-I) reconstituted with phosphatidylcholine, is known to cause a dramatic rise in small high-density lipoprotein (HDL). OBJECTIVE: To explore the mechanisms by which the formation of small HDL particles is induced by CSL112. METHODS AND RESULTS: Infusi...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Didichenko, Svetlana A., Navdaev, Alexei V., Cukier, Alexandre M.O., Gille, Andreas, Schuetz, Patrick, Spycher, Martin O., Thérond, Patrice, Chapman, M. John, Kontush, Anatol, Wright, Samuel D.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
Assuntos:
Integrative Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006797/
https://ncbi.nlm.nih.gov/pubmed/27436846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308685
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