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Effects of Toll-Like Receptor 4 Inhibition on Transforming Growth Factor-β2 Signaling in the Human Trabecular Meshwork

Purpose: Transforming growth factor-β2 (TGFβ2) and Toll-like receptor 4 (TLR4) crosstalk have been implicated in extracellular matrix regulation in the trabecular meshwork (TM) and ocular hypertension in mice. We investigated TLR4 expression in normal and glaucomatous human trabecular meshwork (HTM)...

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Détails bibliographiques
Publié dans:J Ocul Pharmacol Ther
Auteurs principaux: Sharma, Tasneem P., Curry, Stacy, McDowell, Colleen M.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc., publishers 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175615/
https://ncbi.nlm.nih.gov/pubmed/31834824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2019.0076
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