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Interleukin-6–mediated trans-signaling inhibits transforming growth factor-β signaling in trabecular meshwork cells
Glaucoma is one of the major causes of blindness, and transforming growth factor-β2 (TGF-β2) has been found to be elevated in the aqueous humor of eyes with primary open-angle glaucoma (POAG). TGF-β2 in aqueous humor causes the glaucoma-related fibrosis of human trabecular meshwork (HTM), suggesting...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6052206/ https://ncbi.nlm.nih.gov/pubmed/29752408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003298 |
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