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Protein Structure Prediction and Design in a Biologically Realistic Implicit Membrane

Protein design is a powerful tool for elucidating mechanisms of function and engineering new therapeutics and nanotechnologies. Although soluble protein design has advanced, membrane protein design remains challenging because of difficulties in modeling the lipid bilayer. In this work, we developed...

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Vydáno v:Biophys J
Hlavní autoři: Alford, Rebecca F., Fleming, Patrick J., Fleming, Karen G., Gray, Jeffrey J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175592/
https://ncbi.nlm.nih.gov/pubmed/32224301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.03.006
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