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Improved Protocol for the Production of the Low-Expression Eukaryotic Membrane Protein Human Aquaporin 2 in Pichia pastoris for Solid-State NMR

Solid-state nuclear magnetic resonance (SSNMR) is a powerful biophysical technique for studies of membrane proteins; it requires the incorporation of isotopic labels into the sample. This is usually accomplished through over-expression of the protein of interest in a prokaryotic or eukaryotic host i...

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Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Munro, Rachel, de Vlugt, Jeffrey, Ladizhansky, Vladimir, Brown, Leonid S.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175339/
https://ncbi.nlm.nih.gov/pubmed/32168846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10030434
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