Interactions Under Crowding Milieu: Chemical-Induced Denaturation of Myoglobin is Determined by the Extent of Heme Dissociation on Interaction with Crowders

Generally, in vivo function and structural changes are studied by probing proteins in a dilute solution under in vitro conditions, which is believed to be mimicking proteins in intracellular milieu. Earlier, thermal-induced denaturation of myoglobin, in the milieu of crowder molecule showed destabil...

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Veröffentlicht in:Biomolecules
Hauptverfasser: Nasreen, Khalida, Parray, Zahoor Ahmad, Ahamad, Shahzaib, Ahmad, Faizan, Ahmed, Anwar, Freeh Alamery, Salman, Hussain, Tajamul, Hassan, Md. Imtaiyaz, Islam, Asimul
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175338/
https://ncbi.nlm.nih.gov/pubmed/32210191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10030490
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