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NAD- and NADPH-Contributing Enzymes as Therapeutic Targets in Cancer: An Overview
Actively proliferating cancer cells require sufficient amount of NADH and NADPH for biogenesis and to protect cells from the detrimental effect of reactive oxygen species. As both normal and cancer cells share the same NAD biosynthetic and metabolic pathways, selectively lowering levels of NAD(H) an...
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| Publicado no: | Biomolecules |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7175141/ https://ncbi.nlm.nih.gov/pubmed/32111066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10030358 |
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