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Synthesis and Bioactivity of Thiazolethioacetamides as Potential Metallo-β-Lactamase Inhibitors

Metallo-β-lactamase (MβLs) mediated antibiotic resistance seriously threatens the treatment of bacterial diseases. Recently, we found that thioacetamides can be a potential MβL inhibitor skeleton. In order to improve the information of the skeleton, twelve new thiazolethioacetamides were designed by...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Zhang, Yi-Lin, Yan, Yong, Wang, Xue-Jun, Yang, Ke-Wu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175138/
https://ncbi.nlm.nih.gov/pubmed/32110966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9030099
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