Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion

2p16.3 deletions, involving heterozygous NEUREXIN1 (NRXN1) deletion, dramatically increase the risk of developing neurodevelopmental disorders, including autism and schizophrenia. We have little understanding of how NRXN1 heterozygosity increases the risk of developing these disorders, particularly...

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Detalhes bibliográficos
Publicado no:Cereb Cortex
Main Authors: B Hughes, Rebecca, Whittingham-Dowd, Jayde, Simmons, Rachel E, Clapcote, Steven J, Broughton, Susan J, Dawson, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175007/
https://ncbi.nlm.nih.gov/pubmed/31812984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhz244
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