Isoproterenol Increases Left Atrial Fibrosis and Susceptibility to Atrial Fibrillation by Inducing Atrial Ischemic Infarction in Rats

Left atrial (LA) fibrosis is a major arrhythmogenic substrate for atrial fibrillation (AF). The purpose of this study was to assess whether isoproterenol (ISO) induces LA fibrosis and increases susceptibility to AF, exploring the underlying mechanisms. Male Sprague-Dawley rats were subcutaneously in...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Ma, Shiyu, Ma, Jin, Tu, Qingqiang, Zheng, Chaoyang, Chen, Qiuxiong, Lv, Weihui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174760/
https://ncbi.nlm.nih.gov/pubmed/32351393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00493
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