Isoproterenol Increases Left Atrial Fibrosis and Susceptibility to Atrial Fibrillation by Inducing Atrial Ischemic Infarction in Rats

Left atrial (LA) fibrosis is a major arrhythmogenic substrate for atrial fibrillation (AF). The purpose of this study was to assess whether isoproterenol (ISO) induces LA fibrosis and increases susceptibility to AF, exploring the underlying mechanisms. Male Sprague-Dawley rats were subcutaneously in...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Ma, Shiyu, Ma, Jin, Tu, Qingqiang, Zheng, Chaoyang, Chen, Qiuxiong, Lv, Weihui
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174760/
https://ncbi.nlm.nih.gov/pubmed/32351393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00493
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