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Pregabalin as a Pain Therapeutic: Beyond Calcium Channels

Initially developed to generate new treatments for epilepsy, gabapentin, and pregabalin (“gabapentinoids”) were engineered to mimic the action of GABA and to modulate GABA metabolism. Rather than their intended pharmacological action on GABA neurotransmission, instead, they exhibit a high affinity f...

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Détails bibliographiques
Publié dans:Front Cell Neurosci
Auteurs principaux: Alles, Sascha R. A., Cain, Stuart M., Snutch, Terrance P.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174704/
https://ncbi.nlm.nih.gov/pubmed/32351366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00083
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