Pregabalin as a Pain Therapeutic: Beyond Calcium Channels

Initially developed to generate new treatments for epilepsy, gabapentin, and pregabalin (“gabapentinoids”) were engineered to mimic the action of GABA and to modulate GABA metabolism. Rather than their intended pharmacological action on GABA neurotransmission, instead, they exhibit a high affinity f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Neurosci
Prif Awduron: Alles, Sascha R. A., Cain, Stuart M., Snutch, Terrance P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Cellular Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174704/
https://ncbi.nlm.nih.gov/pubmed/32351366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00083
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