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Pregabalin as a Pain Therapeutic: Beyond Calcium Channels

Initially developed to generate new treatments for epilepsy, gabapentin, and pregabalin (“gabapentinoids”) were engineered to mimic the action of GABA and to modulate GABA metabolism. Rather than their intended pharmacological action on GABA neurotransmission, instead, they exhibit a high affinity f...

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Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Alles, Sascha R. A., Cain, Stuart M., Snutch, Terrance P.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174704/
https://ncbi.nlm.nih.gov/pubmed/32351366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00083
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