The EAG Voltage-Dependent K(+) Channel Subfamily: Similarities and Differences in Structural Organization and Gating

EAG (ether-à-go-go or KCNH) are a subfamily of the voltage-gated potassium (Kv) channels. Like for all potassium channels, opening of EAG channels drives the membrane potential toward its equilibrium value for potassium, thus setting the resting potential and repolarizing action potentials. As volta...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Autores principales: Barros, Francisco, de la Peña, Pilar, Domínguez, Pedro, Sierra, Luisa Maria, Pardo, Luis A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174612/
https://ncbi.nlm.nih.gov/pubmed/32351384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00411
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