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The EAG Voltage-Dependent K(+) Channel Subfamily: Similarities and Differences in Structural Organization and Gating

EAG (ether-à-go-go or KCNH) are a subfamily of the voltage-gated potassium (Kv) channels. Like for all potassium channels, opening of EAG channels drives the membrane potential toward its equilibrium value for potassium, thus setting the resting potential and repolarizing action potentials. As volta...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Barros, Francisco, de la Peña, Pilar, Domínguez, Pedro, Sierra, Luisa Maria, Pardo, Luis A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174612/
https://ncbi.nlm.nih.gov/pubmed/32351384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00411
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