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CD73's Potential as an Immunotherapy Target in Gastrointestinal Cancers

CD73, a cell surface 5′nucleotidase that generates adenosine, has emerged as an attractive therapeutic target for reprogramming cancer cells and the tumor microenvironment to dampen antitumor immune cell evasion. Decades of studies have paved the way for these findings, starting with the discovery o...

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Podrobná bibliografie
Vydáno v:Front Immunol
Hlavní autoři: Harvey, Jerry B., Phan, Luan H., Villarreal, Oscar E., Bowser, Jessica L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174602/
https://ncbi.nlm.nih.gov/pubmed/32351498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00508
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