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Metabolism of Glutathione S-Conjugates: Multiple Pathways

Many potentially toxic electrophilic xenobiotics and some endogenous compounds are detoxified by conversion to the corresponding glutathione S-conjugate, which is metabolized to the N-acetylcysteine S-conjugate (mercapturate) and excreted. Some mercapturate pathway components, however, are toxic. Bi...

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Publicat a:Comprehensive Toxicology
Autors principals: Cooper, A.J.L., Hanigan, M.H.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7173497/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-801238-3.01973-5
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