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Metabolism of Glutathione S-Conjugates: Multiple Pathways
Many potentially toxic electrophilic xenobiotics and some endogenous compounds are detoxified by conversion to the corresponding glutathione S-conjugate, which is metabolized to the N-acetylcysteine S-conjugate (mercapturate) and excreted. Some mercapturate pathway components, however, are toxic. Bi...
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| Publicado no: | Comprehensive Toxicology |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7173497/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-801238-3.01973-5 |
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