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Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones

Lysates of cultured cells have been analyzed for arginine-specific endoproteases using peptidyl-p-n itroanil ides as chromogenic substrates. The enzymes present in MDBK, MDCK, VERO, BHK, and chick embryo cells required lysinearginine or arginine-arginine pairs as cleavage sites, whereas chorioallant...

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Publicado en:Virology
Autores principales: Garten, Wolfgang, Stieneke, Andrea, Shaw, Elliott, Wikstrom, Peter, Klenk, Hans-Dieter
Formato: Artigo
Lenguaje:Inglês
Publicado: Published by Elsevier Inc. 1989
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7173068/
https://ncbi.nlm.nih.gov/pubmed/2773317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0042-6822(89)90103-7
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