The α(1,2)‐mannosidase I inhibitor 1‐deoxymannojirimycin potentiates the antiviral activity of carbohydrate‐binding agents against wild‐type and mutant HIV‐1 strains containing glycan deletions in gp120

Exposure of carbohydrate‐binding agents (CBAs) (i.e. the mannose‐specific plant lectins Hippeastrum hybrid agglutinin and Galanthus nivalis agglutinin) to HIV‐1 progressively select for mutant HIV‐1 strains that contain N‐glycan deletions in their envelope gp120. This results in resistance of the mu...

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Vydáno v:FEBS Lett
Hlavní autor: Balzarini, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2007
Témata:
Short Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7173009/
https://ncbi.nlm.nih.gov/pubmed/17475258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.04.039
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