Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial

BACKGROUND: The Middle East respiratory syndrome coronavirus (MERS-CoV) causes a respiratory disease with a case fatality rate of up to 35%. Given its potential to cause a public health emergency and the absence of efficacious drugs or vaccines, MERS is one of the WHO priority diseases warranting ur...

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Vydáno v:Lancet Infect Dis
Hlavní autoři: Koch, Till, Dahlke, Christine, Fathi, Anahita, Kupke, Alexandra, Krähling, Verena, Okba, Nisreen M A, Halwe, Sandro, Rohde, Cornelius, Eickmann, Markus, Volz, Asisa, Hesterkamp, Thomas, Jambrecina, Alen, Borregaard, Saskia, Ly, My L, Zinser, Madeleine E, Bartels, Etienne, Poetsch, Joseph S H, Neumann, Reza, Fux, Robert, Schmiedel, Stefan, Lohse, Ansgar W, Haagmans, Bart L, Sutter, Gerd, Becker, Stephan, Addo, Marylyn M
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Ltd. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7172913/
https://ncbi.nlm.nih.gov/pubmed/32325037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(20)30248-6
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