Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection

Importin-α adaptor proteins orchestrate dynamic nuclear transport processes involved in cellular homeostasis. Here, we show that importin-α3, one of the main NF-κB transporters, is the most abundantly expressed classical nuclear transport factor in the mammalian respiratory tract. Importin-α3 promot...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Thiele, Swantje, Stanelle-Bertram, Stephanie, Beck, Sebastian, Kouassi, Nancy Mounogou, Zickler, Martin, Müller, Martin, Tuku, Berfin, Resa-Infante, Patricia, van Riel, Debby, Alawi, Malik, Günther, Thomas, Rother, Franziska, Hügel, Stefanie, Reimering, Susanne, McHardy, Alice, Grundhoff, Adam, Brune, Wolfram, Osterhaus, Albert, Bader, Michael, Hartmann, Enno, Gabriel, Gülsah
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Author(s). 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7172908/
https://ncbi.nlm.nih.gov/pubmed/32320654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107549
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