Neutrophil Extracellular Trap Induced Dendritic Cell Activation Leads to Th1 Polarization in Type 1 Diabetes

Neutrophils releasing neutrophil extracellular traps (NETs) infiltrate the pancreas prior to type 1 diabetes (T1D) onset; however, the precise nature of their contribution to disease remains poorly defined. To examine how NETs affect immune functions in T1D, we investigated NET composition and their...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Parackova, Zuzana, Zentsova, Irena, Vrabcova, Petra, Klocperk, Adam, Sumnik, Zdenek, Pruhova, Stepanka, Petruzelkova, Lenka, Hasler, Robert, Sediva, Anna
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7172866/
https://ncbi.nlm.nih.gov/pubmed/32346380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00661
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