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α(1)-Antitrypsin and the serpins: variation and countervariation

α(1)-Antitrypsin is a plasma protein which protects elastic tissue from proteolytic attack. Consequently, genetic deficiency, or the oxidation of its reactive centre in cigarette smokers can result in the degenerative lung disease emphysema. Structural studies explain the mechanisms involved and hav...

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Foilsithe in:Trends Biochem Sci
Main Authors: Carrell, Robin, Travis, James
Formáid: Artigo
Teanga:Inglês
Foilsithe: Published by Elsevier Ltd. 1985
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7172600/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0968-0004(85)90011-8
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