Reduction of SOST gene promotes bone formation through the Wnt/β‐catenin signalling pathway and compensates particle‐induced osteolysis

The increase in bone resorption and/or the inhibition of bone regeneration caused by wear particles are the main causes of periprosthetic osteolysis. The SOST gene and Sclerostin, a protein synthesized by the SOST gene, are the characteristic marker of osteocytes and regulate bone formation and reso...

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Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Zhang, Zai Hang, Jia, Xin Yu, Fang, Jing Yi, Chai, Hao, Huang, Qun, She, Chang, Jia, Peng, Geng, De Chun, Xu, Wei
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171346/
https://ncbi.nlm.nih.gov/pubmed/32134561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15084
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