In Utero Treatment of Myelomeningocele with Placental Mesenchymal Stromal Cells-Selection of an Optimal Cell Line In Preparation for Clinical Trials

BACKGROUND: We determined whether in vitro potency assays inform which placental mesenchymal stromal cell (PMSC) lines produce high rates of ambulation following in utero treatment of myelomeningocele in an ovine model. METHODS: PMSC lines were created following explant culture of three early-gestat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Pediatr Surg
Prif Awduron: Galganski, Laura A, Kumar, Priyadarsini, Vanover, Melissa A, Pivetti, Christopher D, Anderson, Jamie E, Lankford, Lee, Paxton, Zachary J, Chung, Karen, Lee, Chelsey, Hegazi, Mennatalla S, Yamashiro, Kaeli J, Wang, Aijun, Farmer, Diana L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170747/
https://ncbi.nlm.nih.gov/pubmed/31672407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2019.09.029
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