In Utero Treatment of Myelomeningocele with Placental Mesenchymal Stromal Cells-Selection of an Optimal Cell Line In Preparation for Clinical Trials

BACKGROUND: We determined whether in vitro potency assays inform which placental mesenchymal stromal cell (PMSC) lines produce high rates of ambulation following in utero treatment of myelomeningocele in an ovine model. METHODS: PMSC lines were created following explant culture of three early-gestat...

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Vydáno v:J Pediatr Surg
Hlavní autoři: Galganski, Laura A, Kumar, Priyadarsini, Vanover, Melissa A, Pivetti, Christopher D, Anderson, Jamie E, Lankford, Lee, Paxton, Zachary J, Chung, Karen, Lee, Chelsey, Hegazi, Mennatalla S, Yamashiro, Kaeli J, Wang, Aijun, Farmer, Diana L
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170747/
https://ncbi.nlm.nih.gov/pubmed/31672407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2019.09.029
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