Multicomponent diffusion analysis reveals microstructural alterations in spinal cord of a mouse model of amyotrophic lateral sclerosis ex vivo

The microstructure changes associated with degeneration of spinal axons in amyotrophic lateral sclerosis (ALS) may be reflected in altered water diffusion properties, potentially detectable with diffusion-weighted (DW) MRI. Prior work revealed the classical mono-exponential model fails to precisely...

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Publicat a:PLoS One
Autors principals: Gao, Jin, Jiang, Mingchen, Magin, Richard L., Gatto, Rodolfo G., Morfini, Gerardo, Larson, Andrew C., Li, Weiguo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170503/
https://ncbi.nlm.nih.gov/pubmed/32310954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231598
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