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Multicomponent diffusion analysis reveals microstructural alterations in spinal cord of a mouse model of amyotrophic lateral sclerosis ex vivo

The microstructure changes associated with degeneration of spinal axons in amyotrophic lateral sclerosis (ALS) may be reflected in altered water diffusion properties, potentially detectable with diffusion-weighted (DW) MRI. Prior work revealed the classical mono-exponential model fails to precisely...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Gao, Jin, Jiang, Mingchen, Magin, Richard L., Gatto, Rodolfo G., Morfini, Gerardo, Larson, Andrew C., Li, Weiguo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170503/
https://ncbi.nlm.nih.gov/pubmed/32310954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231598
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