Gene expression dynamic analysis reveals co-activation of Sonic Hedgehog and epidermal growth factor followed by dynamic silencing

Aberrant activation of the Sonic Hedgehog (SHH) gene is observed in various cancers. Previous studies have shown a “cross-talk” effect between the canonical Hedgehog signaling pathway and the Epidermal Growth Factor (EGF) pathway when SHH is active in the presence of EGF. However, the precise mechan...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Maroufy, Vahed, Shah, Pankil, Asghari, Arvand, Deng, Nan, Le, Rosemarie N.U., Ramirez, Juan C., Yaseen, Ashraf, Zheng, W. Jim, Umetani, Michihisa, Wu, Hulin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170495/
https://ncbi.nlm.nih.gov/pubmed/32341755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27547
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