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High-Resolution Enabled 5-plex Mass Defect-based N,N-Dimethyl Leucine Tags for Quantitative Proteomics

Mass defect-based labeling strategy provides high accuracy as an MS(1)-centric quantification method, avoiding the ratio compression that affects isobaric label-based reporter ion quantification. We have developed cost-effective 5-plex mass defect N,N-dimethyl leucine (mdDiLeu) tags for quantificati...

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Bibliographic Details
Published in:Anal Chem
Main Authors: Zhong, Xiaofang, Frost, Dustin C., Li, Lingjun
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170397/
https://ncbi.nlm.nih.gov/pubmed/31135137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b01691
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