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N, N-Dimethyl Leucines as Novel Isobaric Tandem Mass Tags for Quantitative Proteomics and Peptidomics

Herein we describe the development and application of a set of novel N, N-dimethyl leucine (DiLeu) 4-plex isobaric tandem mass (MS(2)) tagging reagents with high quantitation efficacy and greatly reduced cost for neuropeptide and protein analysis. DiLeu reagents serve as attractive alternatives for...

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Detalhes bibliográficos
Main Authors: Xiang, Feng, Ye, Hui, Chen, Ruibing, Fu, Qiang, Li, Lingjun
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859709/
https://ncbi.nlm.nih.gov/pubmed/20218596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac902778d
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