Novel sulindac derivatives: synthesis, characterisation, evaluation of antioxidant, analgesic, anti-inflammatory, ulcerogenic and COX-2 inhibition activity

A new series of N′-(substituted phenyl)-2-(1-(4-(methylsulfinyl) benzylidene)−5-fluoro-2-methyl-1H-inden-3-yl) acetohydrazide derivatives (1 – 25) were prepared in good yields in an efficient manner. All the compounds were fully characterised by the elemental analysis and spectral data. Synthesised...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Enzyme Inhib Med Chem
Auteurs principaux: Bhat, Mashooq A., Al-Omar, Mohamed A., Alsaif, Nawaf A., Almehizia, Abdulrahman A., Naglah, Ahmed M., Razak, Suhail, Khan, Azmat Ali, Ashraf, Naeem Mahmood
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170310/
https://ncbi.nlm.nih.gov/pubmed/32238055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1746783
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