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Metformin Enhances the Differentiation of Dental Pulp Cells into Odontoblasts by Activating AMPK Signaling

INTRODUCTION: Metformin is a first-line drug for treating type 2 diabetes that regulates the differentiation of mesenchymal stem cells. Its effects on human dental pulp cells (DPCs) remain unknown. This study aimed to investigate the effects of metformin on proliferation and differentiation of DPCs....

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Bibliographic Details
Published in:J Endod
Main Authors: Qin, Wei, Gao, Xianling, Ma, Tao, Weir, Michael D., Zou, Jing, Song, Bing, Lin, Zhengmei, Schneider, Abraham, Xu, Hockin H. K.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7169970/
https://ncbi.nlm.nih.gov/pubmed/29306537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joen.2017.11.017
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