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Metformin Enhances the Differentiation of Dental Pulp Cells into Odontoblasts by Activating AMPK Signaling

INTRODUCTION: Metformin is a first-line drug for treating type 2 diabetes that regulates the differentiation of mesenchymal stem cells. Its effects on human dental pulp cells (DPCs) remain unknown. This study aimed to investigate the effects of metformin on proliferation and differentiation of DPCs....

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Publicat a:J Endod
Autors principals: Qin, Wei, Gao, Xianling, Ma, Tao, Weir, Michael D., Zou, Jing, Song, Bing, Lin, Zhengmei, Schneider, Abraham, Xu, Hockin H. K.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7169970/
https://ncbi.nlm.nih.gov/pubmed/29306537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joen.2017.11.017
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