Suberoylanilide hydroxamic acid alleviates orthotopic liver transplantation-induced hepatic ischemia-reperfusion injury by regulating the AKT/GSK3β/NF-κB and AKT/mTOR pathways in rat Kupffer cells

Multiple mechanisms are involved in regulating hepatic ischemia-reperfusion injury (IRI), in which Kupffer cells (KCs), which are liver-resident macrophages, play critical roles by regulating inflammation and the immune response. Suberoylanilide hydroxamic acid (SAHA), a pan-histone deacetylase inhi...

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Publicado no:Int J Mol Med
Main Authors: Wang, Jingyuan, Deng, Minghua, Wu, Hao, Wang, Menghao, Gong, Jianping, Bai, He, Wu, Yakun, Pan, Junjiang, Chen, Yong, Li, Shengwei
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7169828/
https://ncbi.nlm.nih.gov/pubmed/32236599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2020.4551
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