Ligustrazine ameliorates lipopolysaccharide-induced neurocognitive impairment by activating autophagy via the PI3K/AKT/mTOR pathway

Autophagy is a lysosome-mediated cell content- dependent degradation pathway that leads to enhanced inflammation in an uncontrolled state. This study examined the role of autophagy in lipopolysaccharide (LPS)-induced brain inflammation and the effects of the traditional Chinese medicine ligustrazine...

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Published in:Int J Mol Med
Main Authors: Li, Guangming, Liu, Sisi, Wang, Huili, Pan, Rui, Tang, Haijie, Yan, Xueqin, Wang, Yanping, Fu, Yongmei, Jing, Fujun, Dong, Jun
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7169653/
https://ncbi.nlm.nih.gov/pubmed/32236586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2020.4548
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