NF-κB1 Regulates Immune Environment and Outcome of Notch-Dependent T-Cell Acute Lymphoblastic Leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive pediatric malignancy that arises from the transformation of immature T-cell progenitors and has no definitive cure. Notch signaling governs many steps of T cell development and its dysregulation represents the most common causative event i...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Grazioli, Paola, Orlando, Andrea, Giordano, Nike, Noce, Claudia, Peruzzi, Giovanna, Scafetta, Gaia, Screpanti, Isabella, Campese, Antonio Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7169422/
https://ncbi.nlm.nih.gov/pubmed/32346377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00541
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