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Synthetic Simplification of Carolacton Enables Chemical Genetic Studies in Streptococcus mutans

Understanding the broader biological impact of carolacton, a macrolactone natural product, has been ongoing for the past decade. Multiple studies have shown connections to regulatory systems, acid tolerance mechanisms, biofilm formation, and recently folate dehydrogenase (FolD). Progress elucidating...

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Bibliografische gegevens
Gepubliceerd in:ACS Infect Dis
Hoofdauteurs: Solinski, Amy E., Scharnow, Amber M., Fraboni, Americo J., Wuest, William M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7169375/
https://ncbi.nlm.nih.gov/pubmed/31243986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00213
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