Diverted Total Synthesis of Carolacton-Inspired Analogs Yields Three Distinct Phenotypes in Streptococcus mutans Biofilms

The oral microbiome is a dynamic environment inhabited by both commensals and pathogens. Among these is Streptococcus mutans, the causative agent of dental caries, the most prevalent childhood disease. Carolacton has remarkably specific activity against S. mutans, causing acid-mediated cell death du...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Am Chem Soc
Main Authors: Solinski, Amy E., Koval, Alexander B., Brzozowski, Richard S., Morrison, Kelly R., Fraboni, Americo J., Carson, Carrie E., Eshraghi, Anisa R., Zhou, Guangfeng, Quivey, Robert G., Voelz, Vincent A, Buttaro, Bettina A., Wuest, William M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891724/
https://ncbi.nlm.nih.gov/pubmed/28502178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b03879
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla