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Family Study Designs to Combat Heterogeneity and Identify Multi-Cancer Pleiotropies: The Power of the Utah Population Database
BACKGROUND: Previously, family-based designs and high-risk pedigrees have illustrated value for the discovery of high- and intermediate-risk germline breast cancer susceptibility genes. However, genetic heterogeneity is a major obstacle hindering progress. New strategies and analytic approaches will...
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| Publicado no: | Cancer Epidemiol Biomarkers Prev |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7168701/ https://ncbi.nlm.nih.gov/pubmed/32098891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-19-0912 |
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