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CoMFA/CoMSIA/HQSAR and Docking Study of the Binding Mode of Selective Cyclooxygenase (COX‐2) Inhibitors

The intermolecular interaction between four types of anti‐inflammatory inhibitors (oxazoles, pyrazoles, pyrroles and imidazoles) and COX‐2 receptor was studied. The results of docking suggest that they have similar interaction mechanism. The most active compounds of these four types of inhibitors co...

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Bibliografiske detaljer
Udgivet i:QSAR Comb Sci
Main Authors: Chen, Haifeng, Li, Qiang, Yao, Xiaojun, Fan, BoTao, Yuan, Shengang, Panaye, A., Doucet, J. P.
Format: Artigo
Sprog:Inglês
Udgivet: WILEY‐VCH Verlag 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168538/
https://ncbi.nlm.nih.gov/pubmed/32327948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/qsar.200330844
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