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CoMFA/CoMSIA/HQSAR and Docking Study of the Binding Mode of Selective Cyclooxygenase (COX‐2) Inhibitors

The intermolecular interaction between four types of anti‐inflammatory inhibitors (oxazoles, pyrazoles, pyrroles and imidazoles) and COX‐2 receptor was studied. The results of docking suggest that they have similar interaction mechanism. The most active compounds of these four types of inhibitors co...

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Dettagli Bibliografici
Pubblicato in:QSAR Comb Sci
Autori principali: Chen, Haifeng, Li, Qiang, Yao, Xiaojun, Fan, BoTao, Yuan, Shengang, Panaye, A., Doucet, J. P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: WILEY‐VCH Verlag 2004
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168538/
https://ncbi.nlm.nih.gov/pubmed/32327948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/qsar.200330844
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