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The dual role of thymidine phosphorylase in cancer development and chemotherapy

Thymidine phosphorylase (TP), also known as “platelet‐derived endothelial cell growth factor” (PD‐ECGF), is an enzyme, which is upregulated in a wide variety of solid tumors including breast and colorectal cancers. TP promotes tumor growth and metastasis by preventing apoptosis and inducing angiogen...

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Detalhes bibliográficos
Publicado no:Med Res Rev
Main Authors: Bronckaers, Annelies, Gago, Federico, Balzarini, Jan, Liekens, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168469/
https://ncbi.nlm.nih.gov/pubmed/19434693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.20159
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