Gold nanoparticle‐adjuvanted S protein induces a strong antigen‐specific IgG response against severe acute respiratory syndrome‐related coronavirus infection, but fails to induce protective antibodies and limit eosinophilic infiltration in lungs

The spike (S) protein of coronavirus, which binds to cellular receptors and mediates membrane fusion for cell entry, is a candidate vaccine target for blocking coronavirus infection. However, some animal studies have suggested that inadequate immunization against severe acute respiratory syndrome co...

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Bibliographische Detailangaben
Veröffentlicht in:Microbiol Immunol
Hauptverfasser: Sekimukai, Hanako, Iwata‐Yoshikawa, Naoko, Fukushi, Shuetsu, Tani, Hideki, Kataoka, Michiyo, Suzuki, Tadaki, Hasegawa, Hideki, Niikura, Kenichi, Arai, Katsuhiko, Nagata, Noriyo
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168429/
https://ncbi.nlm.nih.gov/pubmed/31692019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1348-0421.12754
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