Gold nanoparticle‐adjuvanted S protein induces a strong antigen‐specific IgG response against severe acute respiratory syndrome‐related coronavirus infection, but fails to induce protective antibodies and limit eosinophilic infiltration in lungs

The spike (S) protein of coronavirus, which binds to cellular receptors and mediates membrane fusion for cell entry, is a candidate vaccine target for blocking coronavirus infection. However, some animal studies have suggested that inadequate immunization against severe acute respiratory syndrome co...

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Detalhes bibliográficos
Publicado no:Microbiol Immunol
Main Authors: Sekimukai, Hanako, Iwata‐Yoshikawa, Naoko, Fukushi, Shuetsu, Tani, Hideki, Kataoka, Michiyo, Suzuki, Tadaki, Hasegawa, Hideki, Niikura, Kenichi, Arai, Katsuhiko, Nagata, Noriyo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168429/
https://ncbi.nlm.nih.gov/pubmed/31692019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1348-0421.12754
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