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Generating Vesicular Stomatitis Virus Pseudotype Bearing the Severe Acute Respiratory Syndrome Coronavirus Spike Envelope Glycoprotein for Rapid and Safe Neutralization Test or Cell‐Entry Assay

abstract:  We generated a recombinant vesicular stomatitis virus (VSV) pseudotype (VSV Δ G*SG) by replacing the envelope G gene with the GFP gene and complementing with spike glycoprotein (S) of SARS‐CoV in trans. The neutralization and infection blocking tests showed that the VSV Δ G*SG and SARS‐Co...

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Publicat a:Ann N Y Acad Sci
Autors principals: GE, JINYING, WEN, ZHIYUN, WANG, XIJUN, HU, SEN, LIU, YONGGANG, KONG, XIANGANG, CHEN, HUALAN, BU, ZHIGAO
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Inc 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167956/
https://ncbi.nlm.nih.gov/pubmed/17135519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1373.030
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