Generating Vesicular Stomatitis Virus Pseudotype Bearing the Severe Acute Respiratory Syndrome Coronavirus Spike Envelope Glycoprotein for Rapid and Safe Neutralization Test or Cell‐Entry Assay

abstract:  We generated a recombinant vesicular stomatitis virus (VSV) pseudotype (VSV Δ G*SG) by replacing the envelope G gene with the GFP gene and complementing with spike glycoprotein (S) of SARS‐CoV in trans. The neutralization and infection blocking tests showed that the VSV Δ G*SG and SARS‐Co...

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Bibliographic Details
Published in:Ann N Y Acad Sci
Main Authors: GE, JINYING, WEN, ZHIYUN, WANG, XIJUN, HU, SEN, LIU, YONGGANG, KONG, XIANGANG, CHEN, HUALAN, BU, ZHIGAO
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Inc 2006
Subjects:
Part II. Trends in the Study of Disease Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167956/
https://ncbi.nlm.nih.gov/pubmed/17135519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1373.030
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