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Interleukin‐18: Biological properties and role in disease pathogenesis

Initially described as an interferon (IFN)γ‐inducing factor, interleukin (IL)‐18 is indeed involved in Th1 and NK cell activation, but also in Th2, IL‐17‐producing γδ T cells and macrophage activation. IL‐18, a member of the IL‐1 family, is similar to IL‐1β for being processed by caspase 1 to an 18 ...

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Detalhes bibliográficos
Publicado no:Immunol Rev
Autor principal: Kaplanski, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165732/
https://ncbi.nlm.nih.gov/pubmed/29247988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12616
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