Interleukin-18 and IL-18 Binding Protein

Interleukin-18 (IL-18) is a member of the IL-1 family of cytokines. Similar to IL-1β, IL-18 is synthesized as an inactive precursor requiring processing by caspase-1 into an active cytokine but unlike IL-1β, the IL-18 precursor is constitutively present in nearly all cells in healthy humans and anim...

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Bibliographic Details
Main Authors: Dinarello, Charles A., Novick, Daniela, Kim, Soohyun, Kaplanski, Gilles
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792554/
https://ncbi.nlm.nih.gov/pubmed/24115947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00289
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